Napoli v Inter Milan – Preview, Predictions and Best Bets

The hosts have lost four of their last seven matches. Inter are on a seven-match winning streak with five clean sheets. Inter have lost just one of their last 13 clashes vs Napoli.

Match: Napoli v Inter Milan
When: Saturday, 25 Oct 2025

Napoli Form

The Partenopei sit third in Serie A with five wins and two draws in seven rounds of action. They won their first three matches this season in all competitions but have since lost four of the last seven. A 2-0 loss at Man City came with ten men. A 3-2 win followed over Pisa.

Napoli lost 2-1 at ten-man AC Milan despite having a man more for 33 minutes. A Rasmus Hojlund brace saw a 2-1 win over Sporting Lison before beating Genoa 2-1. Antonio Conte’s side have lost their last two matches. A 1-0 loss at Torino came with 22 shots and 69% possession. In midweek, they lost 6-2 at PSV after allowing six big chances.

Napoli Team News

There are five injuries for this match. Romelu Lukaku is ruled out and Rasmus Hojlund is a serious dobut, with Lorenzo Lucca on standby to deputise despite his midweek red card.

Centre back Amir Rrahmani is highly doubtful with a hamstring injury and Stanislav Lobotka is also expected to miss out. Backup goalkeeper Nikita Contini is out injured.

Napoli Motivation

Conte’s side seems to have lost some confidence. They’re a mess defensively and are missing plenty of chances. This is a must-not-lose match.

Expect a pragmatic approach. Napoli can’t take many risks right now as they defence suffers when left exposed.

Inter Milan Form

Inter are flying right now with seven wins on the bounce. After losing two of their first three league matches, they’ve found their best form again. A 2-0 win at Ajax in Amsterdam was followed by two Serie A wins: 2-1 at home to Sassuolo and 2-0 at Cagliari.

They beat Slavia Prague 3-0 in the Champions League and smashed Cremonese 4-1 with 3.57 xG. A 1-0 win at Roma was followed by a 4-0 win in midweek at Royal Union St. Gilloise as they created an incredible 4.55 xG and nine big chances from 21 shots in Belgium.

Inter Milan Team News

Marcus Thuram is a doubt up front for this one. Matteo Darmian is also set to miss out with a muscle injury.

Coach Cristian Chivu may recall Mauel Akanji and Federico Dimarco are partial rests in midweek. Youngster Francesco Pio Esposito is set to partner Lautaro Martinez up front.

Inter Milan Motivation

Confidence in the squad is sky-high. Inter are creating chances for fun and will go to Naples aiming for a win.

A positive approach is expected with plenty of possession and lots of players breaking into the box.

Key Stats

• Napoli have lost 4 of their last 7 matches
• Napoli have lost 2 of their last 5 matches vs Inter Milan (last three: all 1-1 draws)
• Inter Milan have lost just 1 of their last 13 matches vs Napoli
• Inter Milan have won their last 7 matches in all competitions

Verdict

On current form, and based on the head-to-head record, Inter will win this match or at least avoid defeat.

Best Bet: Inter Milan win at 2.42

Alternate Bet: Inter Milan win/draw double chance and Both Team to Score at 2.55